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Ritonavir or lopinavir/ritonavir enormously raise plasma concentrations of oxycodone in balanced human volunteers resulting from inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin drastically cuts down plasma concentrations of oxycodone as a consequence of solid induction of CYP3A4.Canadian oxycodone HCL/acetaminophen 5/325 mg tablet In Febru